Mortality Prediction Hidden in our Genome

The success of hematopoietic stem cell transplant (HSCT) is influenced by many factors including HLA mismatches, variations in the major histocompatibility complex (MHC) region, minor histocompatibility targets of allorecognition, regulatory elements that affect gene expression and genetic variation that affects immune responses (Table 1, Table 2). The individual contribution...

 

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It Is Not You Who Chooses Your Partner… But Your HLA Genes!

Written by Nina Lauterbach, PhD (Field Application Scientist, Omixon) Animals, and us humans, are daily under attack by viruses and other pathogens. Fortunately, we are equipped with the Major Histocompatibility Complex (MHC) as an efficient and adaptable fighting mechanism to deal with these threatening events. This complex is encoded...

 

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