Simple, fast and accurate. Now with Full Gene Coverage.
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INTRODUCING NANOTYPE HLA-11 PLUS
Experience the power of true full-gene HLA genotyping with NanoTYPETM HLA-11 Plus—covering all 11 classical loci from 5′UTR to 3′UTR. Seamlessly integrated with (many) ONT’s long-read platforms, it delivers uninterrupted phasing, fast library prep, and unambiguous results—even in highly polymorphic regions.
Product Benefits
COVERAGE
NANOTYPER™ 2.2.0
INTRODUCING OUR INTUITIVE AND USER-FRIENDLY SOFTWARE:
✓ UP TO 4th FIELD RESOLUTION
✓ NOISE TRACK
✓ PHASING INFORMATION
✓ AUTOMATED ANALYSIS
✓ FAST ANALYSIS WITH 2 MINUTES PER SAMPLE
Example of full phasing of DPB1*01:01:01:01 / 04:01:01:01
Thanks to the design of Tube 2, which spans from the 5’UTR to intron 2 and overlaps with Tube 1, full-gene phasing is achieved, resulting in unambiguous allele assignment across the entire gene. Additionally, the Noise Track (top panel) provides a visual representation of the Signal-to-Noise ratio, as well as the allelic balance between the two chromosomes.
Full set of quality control metrics available for every HLA locus
NanoTYPER provides QC metrics per locus, including key exon minimum coverage, allele imbalance, spot noise ratio, and N50 read length. These metrics ensure transparent assessment of sequencing quality and genotyping reliability across all 11 HLA genes.
REGULATORY STATUS
Research Use Only
Omixon Biocomputing Ltd is the legal manufacturer of the NanoTYPE HLA-11 Plus (24) and the NanoTYPE HLA-11 Plus (96) assays and NanoTYPER RUO software products. NanoTYPE HLA-11 Plus, and NanoTYPER are trademarks of Omixon Biocomputing Ltd. NanoTYPE HLA-11 Plus covers the NanoTYPE HLA-11 Plus (24) and the NanoTYPE HLA-11 Plus (96) assays and NanoTYPER RUO software products. MinION®, PromethION ®, and GridION® are registered trademarks of Oxford Nanopore Technologies, the respective images to be credited to Oxford Nanopore Technologies. All Omixon activities covered by an ISO 13485:2016 & EN ISO 13485:2016 Quality Management System (QMS).