HLA Twin ™


  • Two independent algorithms - Consensus Genotyping and Statistical Genotyping
  • Orthogonal validation using two algorithms to obtain the highest possible confidence for every locus of every allele in every sample
  • Analyze data against any version of the IMGT/HLA Database
  • DRB Linkage Disequlibrium checks


  • 23 Quality Metrics for confident assignment and detailed troubleshooting
  • Traffic Light System for easy interpretation of genotyping results
  • Whole Gene Consensus sequences for unambiguous allele assignment
  • Complete Novel and Null allele detection

Automation and Integration

  • Fully automated analysis after Illumina Miseq run
  • Export genotyping results in the standard Histoimmunogenetics Markup Language format (HML 1.0.1) or detailed summary reports in PDF
  • Integration with LIMS systems, Histotrac and mTilda
  • Simple assignment and approval workflows

Flexibility & Scalability

  • Platform independent (available for Windows, Linux and OS X)
  • Desktop and Client-Server versions
  • Customizable analysis and visualization
  • 96 samples for 11 loci can be processed within 10 hours on an 8-core server with 32GB of RAM
Note: HLA Twin is sold as part of Holotype HLA and is not available for download from our website. Please contact support@omixon.com for more information.