Editorial Board Award – Human Immunology

10/05/2022

Each year, the Human Immunology editorial board awards the best original research papers and the best review papers from two years previous. The top papers in each category published in 2020 were chosen based on citation and download statistics gathered from 2021. The papers were then voted on by...

Webinar – Analyzing High-Resolution HLA Typing by NGS – Which Tools Do We Need?

29/04/2020

Join us for a Webinar on Wednesday, 6th May 2020 with Nina Lauterbach (Field Application Scientist, Omixon) who will be talking about the crucial differences between NGS and Sanger sequencing. She is going to highlight the benefits and challenges of NGS based HLA typing, and what tools are...

Holotype HLA Validation on Illumina’s MiniSeq

31/01/2019

Introduction The Illumina NGS sequencing fleet includes instruments of different sample capacity. One of them is the MiniSeq – designed for laboratories with a small to medium sample throughput. Omixon’s Holotype HLA was initially developed and validated for Illumina’s MiSeq, as this is a commonly available instrument in clinical...

Transplantation: What Was and What is Next?

25/01/2017

118 893 33 596 15 591 These are just 3 numbers in the United States to describe transplantation in 2016. According to the annual data of UNOS (United Network for Organ Sharing): 118 893 people needed organ transplant 33 596 transplants performed in 2016 15 591 total number of donors...

PLOS ONE: Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA: Results from over 10,000 Donor Recruitment Samples

04/11/2016

Authors: Yuxin Yin, James H. Lan, David Nguyen, Nicole Valenzuela, Ping Takemura, Yung-Tsi Bolon, Brianna Springer, Katsuyuki Saito, Ying Zheng, Tim Hague, Agnes Pasztor, Gyorgy Horvath, Krisztina Rigo, Elaine F. Reed, Qiuheng Zhang Abstract: Background Unambiguous HLA typing is important in hematopoietic stem cell transplantation (HSCT), HLA disease association studies, and solid organ transplantation. However, current molecular typing methods only...