We recommended storing ExoSAP-IT reagent at -20 °C in a non-frost-free freezer. It can be stable for up to 2 years.

Unfortunately, we do not have data showing how the stability changes with every freeze/thaw cycle, however, our general advice is to make aliquotes when working with enzymes and minimize the number of freeze-thaw cycles. This way you can mitigate the impact of freeze/thaw cycles to minimum.