If there is a run error within the first few minutes of the sequencing run starting (“Run stopped with error”, “Run stopped due to internal error”), you can also Restart the position and set up the run again, or restart the computer entirely (remembering to unplug MinION first). The flow cell and library will not be affected. Ensure also the flow cell is inserted correctly into the device and ensure the device/USB cable is connected properly to the laptop. It is best also to ensure the USB cable is not being strained and that MinION is kept close to the computer – stretching of the cable can lead to disconnection.