A Case Study for HLA Typing in Clinics: Reproducibility and Flowspace Alignment of NGS Reads
Authors: Krisztina Rigó, György Horváth, Szilveszter Juhos, Sabine Canivet, Philippe Pellet, Abdelali Boudifa, Veronique Bertrand, Ioannis Theodorou Abstract: Long reads produced by Roche 454 sequencers are used for HLA typing for quite a while. Having long reads it is easier to determine the phase, but homopolymer errors are bringing in...