High Accuracy and High Precision HLA Typing Using Illumina Reads: Typing Algorithm and Perspectives on Novel Allele Discovery

Authors: György Horváth, Krisztina Rigó, Tim Hague, Attila Bérces, Szilveszter Juhos Abstract: Wide acceptance of high-throughput next-generation sequencers in medicinal genomics and clinics brought the promise of fast HLA typing. We are presenting the algorithmic challenges and workflow of HLA typing with a special attention to ambiguous or poorly...

 

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Immunotherapy

Cancer has become one of the biggest killers in the western world. High profile campaigns to tackle breast cancer and other common types have ensured that it is also one of the biggest businesses in modern medicine. To fight a high profile killer you need the best of cures....

 

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Cancer Biomarkers

When tackling any disease, the first step is to learn what signals its presence and what else these signs can mean. In discussing cancer, these signs are referred to as cancer biomarkers. Some organisations define a biomarker as a molecule that the cancerous tumor has secreted into the body,...

 

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