In the last few years, announcements about revolutionary new sequencing technologies have been popping up like daisies. All of them promised to solve at least some of the problems we have with existing NGS technologies. Some of these new techniques became popular, but several of them either never became commercially available or never gained popularity. To tell you the truth, a sequencer that is not used by a lot of people is very much like a sequencer that doesn’t exist at all.* So here is a list of sequencing platforms that definitely exist: the three biggest players of the NGS field and some honorable mentions.